Invention Grant
US08426579B2 SiRNA targeting myeloid differentiation primary response gene (88) (MYD88)
有权
靶向骨髓分化原发性反应基因(88)(MYD88)
- Patent Title: SiRNA targeting myeloid differentiation primary response gene (88) (MYD88)
- Patent Title (中): 靶向骨髓分化原发性反应基因(88)(MYD88)
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Application No.: US13136812Application Date: 2011-08-11
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Publication No.: US08426579B2Publication Date: 2013-04-23
- Inventor: Anastasia Khvorova , Angela Reynolds , Devin Leake , William Marshall , Steven Read , Stephen Scaringe
- Applicant: Anastasia Khvorova , Angela Reynolds , Devin Leake , William Marshall , Steven Read , Stephen Scaringe
- Applicant Address: US CO Lafayette
- Assignee: Dharmacon, Inc.
- Current Assignee: Dharmacon, Inc.
- Current Assignee Address: US CO Lafayette
- Agency: Dorf & Nelson LLP
- Agent Scott D. Locke, Esq.
- Main IPC: C07H21/00
- IPC: C07H21/00

Abstract:
Efficient sequence specific gene silencing is possible through the use of siRNA technology. By selecting particular siRNAs by rational design, one can maximize the generation of an effective gene silencing reagent, as well as methods for silencing genes. Methods, compositions, and kits generated through rational design of siRNAs are disclosed including those directed to nucleotide sequences for MYD88.
Public/Granted literature
- US20120010106A1 siRNA targeting myeloid differentiation primary response gene (88) (MYD88) Public/Granted day:2012-01-12
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