Invention Grant
- Patent Title: Process for preparing amino crotonyl compounds
- Patent Title (中): 制备氨基巴豆酰化合物的方法
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Application No.: US11457622Application Date: 2006-07-14
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Publication No.: US08426586B2Publication Date: 2013-04-23
- Inventor: Rainer Soyka , Werner Rall , Juergen Schnaubelt , Peter Sieger , Christian Kulinna
- Applicant: Rainer Soyka , Werner Rall , Juergen Schnaubelt , Peter Sieger , Christian Kulinna
- Applicant Address: DE Ingelheim am Rhein
- Assignee: Boehringer Ingelheim International GmbH
- Current Assignee: Boehringer Ingelheim International GmbH
- Current Assignee Address: DE Ingelheim am Rhein
- Agent Michael P. Morris; Anthony P. Bottino
- Priority: DE10349113 20031017
- Main IPC: C07D239/84
- IPC: C07D239/84 ; C07D215/44
Abstract:
An improved process for preparing 4-[(3-chloro-4-fluorophenyl)amino]-6-{[4-(N,N-dimethylamino)-1-oxo-2-buten-1-yl]amino}-7-((S)-tetrahydrofuran-3-yloxy)-quinazoline and related aminocrotonyl compounds and the preparation of a suitable salt of 4-[(3-chloro-4-fluorophenyl)amino]-6-{[4-(N,N-dimethylamino)-1-oxo-2-buten-1-yl]amino}-7-((S)-tetrahydrofuran-3-yloxy)-quinazoline for use as a pharmaceutically active substance.
Public/Granted literature
- US20070027170A1 Process for preparing amino crotonyl compounds Public/Granted day:2007-02-01
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