A dynamically reconfigurable battery framework for management of a large-scale battery system systems is provided. The framework monitors, reconfigures, and controls large-scale battery systems online. The framework is built upon a topology-based bypassing mechanism that provides a set of rules for changing the battery-pack configuration, and a semantic bypassing mechanism by which the battery-cell connectivity is reconfigured to recover from a battery-cell failure. More specifically, the semantic bypassing mechanism implements a constant-voltage-keeping policy and a dynamic-voltage-allowing policy. The former policy is effective in preventing unavoidable voltage drops during the battery lifetime, while the latter policy is effective in supplying different amounts of power to meet a wide-range of application requirements.