An expendable tamper evident seal system for monitoring a mechanism to which physical access is required in order to open or close an access-way, comprising: an embedding material moldable into a shape conforming to the mechanism and adapted to be applied to the mechanism; circuit components randomly embedded in the embedding material so as to be arranged in positions and orientations corresponding to the shape, whereby physical access to the mechanism that alters the shape of the embedding material correspondingly alters the positions and orientations of the circuit components in the material; and an electronic interrogation device (EID) including components that induce in the circuit components an electromagnetic spectral response indicative of the position of the EID relative to the positions and orientations of the circuit components in the material, and measure the spectral response.