Invention Grant
- Patent Title: Multi-component medicine evaluation method
- Patent Title (中): 多组分药物评价方法
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Application No.: US11628764Application Date: 2005-06-06
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Publication No.: US08428883B2Publication Date: 2013-04-23
- Inventor: Kouya Yano , Naoko Hattori
- Applicant: Kouya Yano , Naoko Hattori
- Applicant Address: JP Tokyo
- Assignee: Tsumura & Co.
- Current Assignee: Tsumura & Co.
- Current Assignee Address: JP Tokyo
- Agency: Oblon, Spivak, McClelland, Maier & Neustadt, L.L.P.
- Priority: JP2004/008256 20040607
- International Application: PCT/JP2005/010349 WO 20050606
- International Announcement: WO2005/121777 WO 20051222
- Main IPC: G01N33/48
- IPC: G01N33/48 ; G01N31/00 ; G06G7/48
Abstract:
A method for evaluation of a multi-component medicine by judging the degree of difference of the multi-component medicine to be evaluated from a group of multi-component medicines selected as a reference group by using a Mahalanobis distance obtained by combining the 3D-HPLC fingerprint data of a multi-component medicine with fingerprint data of 3D-HPLC of other multi-component medicines of the same kind forming a reference group, allocating variable axes in the MT method to the number of multi-component medicine and the elution time or detection wavelength of the fingerprint data, obtaining a unit space from the signal strength, and obtaining the Mahalanobis distance of the multi-component medicine from the unit space.
Public/Granted literature
- US20080140375A1 Multi-Component Medicine Evaluation Method Public/Granted day:2008-06-12
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