A recreational vehicle with weatherproofing for a slide-out compartment has a main body, a slide-out compartment having a side wall with an upper wall, a bottom wall and a pair of end walls extending inwardly from the side wall, and a first cover having one end affixed to the side wall of the main body and an opposite end affixed to the slide-out compartment. The first cover extends over top wall and a pair of end walls of the slide-out compartment. The first cover is formed of a flexible watertight material. The first cover is affixed by bracket to the side wall of the main body and to the slide-out compartment. A second cover is affixed to the first cover and extends through a slot formed between the upper wall of the slide-out compartment and the opening of the side wall of the main body.