Invention Grant
US08435749B2 Anti-CDH3 antibodies labeled with radioisotope label and uses thereof
有权
用放射性同位素标记的抗CDH3抗体及其用途
- Patent Title: Anti-CDH3 antibodies labeled with radioisotope label and uses thereof
- Patent Title (中): 用放射性同位素标记的抗CDH3抗体及其用途
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Application No.: US13001869Application Date: 2009-06-30
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Publication No.: US08435749B2Publication Date: 2013-05-07
- Inventor: Akira Togashi , Masakazu Katsu , Megumi Takayanagi , Hiroki Yoshioka , Pohsing Ng , Yasuhiro Shiba , Yusuke Nakamura , Keigo Endo
- Applicant: Akira Togashi , Masakazu Katsu , Megumi Takayanagi , Hiroki Yoshioka , Pohsing Ng , Yasuhiro Shiba , Yusuke Nakamura , Keigo Endo
- Applicant Address: JP Kanagawa
- Assignee: Oncotherapy Science, Inc.
- Current Assignee: Oncotherapy Science, Inc.
- Current Assignee Address: JP Kanagawa
- Agency: Kilpatrick Townsend & Stockton LLP
- International Application: PCT/JP2009/003009 WO 20090630
- International Announcement: WO2010/001585 WO 20100107
- Main IPC: G01N33/53
- IPC: G01N33/53 ; A61K39/395 ; C07K16/00 ; C07K16/28

Abstract:
The present invention relates to anti-CDH3 antibodies, which can be labeled with a radioisotope. Moreover, the present invention provides methods and pharmaceutical compositions that comprise an anti-CDH3 antibody as an active ingredient. Since CDH3 is strongly expressed in pancreatic, lung, colon, prostate, breast, gastric or liver cancer cells, the present invention is useful in pancreatic, lung, colon, prostate, breast, gastric or liver cancer therapies.
Public/Granted literature
- US20120128584A1 ANTI-CDH3 ANTIBODIES LABELED WITH RADIOISOTOPE LABEL AND USES THEREOF Public/Granted day:2012-05-24
Information query
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