Invention Grant
- Patent Title: Mutant Pfu DNA polymerase
- Patent Title (中): 突变型Pfu DNA聚合酶
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Application No.: US12440374Application Date: 2007-08-24
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Publication No.: US08435775B2Publication Date: 2013-05-07
- Inventor: Phillip Holliger , Nicola Ramsay , Ann-Sofie Jemth
- Applicant: Phillip Holliger , Nicola Ramsay , Ann-Sofie Jemth
- Applicant Address: GB Swindon
- Assignee: Medical Research Council
- Current Assignee: Medical Research Council
- Current Assignee Address: GB Swindon
- Agency: Marshall, Gerstein & Borun LLP
- Priority: GB0617565.7 20060906; GB0712157.7 20070622
- International Application: PCT/GB2007/003254 WO 20070824
- International Announcement: WO2008/029085 WO 20080313
- Main IPC: C12N9/00
- IPC: C12N9/00 ; C07H21/02
Abstract:
The present invention relates to an engineered polymerase with an expanded substrate range characterized in that the polymerase is capable of incorporating an enhanced occurrence of detection agent-labeled nucleotide analogue into nucleic acid synthesized by that engineered polymerase as compared with the wild type polymerase from which it is derived.
Public/Granted literature
- US20100035767A1 POLYMERASE Public/Granted day:2010-02-11
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