Invention Grant
- Patent Title: Methods of modulating lipid concentrations in eukaryotic cells
- Patent Title (中): 调节真核细胞中脂质浓度的方法
-
Application No.: US12508853Application Date: 2009-07-24
-
Publication No.: US08435790B2Publication Date: 2013-05-07
- Inventor: Robert V. Farese, Jr. , Yi Guo , Tobias C. Walther , Peter Walter
- Applicant: Robert V. Farese, Jr. , Yi Guo , Tobias C. Walther , Peter Walter
- Applicant Address: US CA Oakland US CA San Francisco
- Assignee: The Regents of the University of California,The J. David Gladstone Institutes
- Current Assignee: The Regents of the University of California,The J. David Gladstone Institutes
- Current Assignee Address: US CA Oakland US CA San Francisco
- Agency: Peters Verny, LLP
- Agent David J. Aston
- Main IPC: C12N15/01
- IPC: C12N15/01
Abstract:
The present invention is based on the discovery of a set of genes that are involved in lipid-droplet formation and regulation. Accordingly, the present invention provides methods of increasing or decreasing lipid concentrations in eukaryotic cells by decreasing or increasing expression of one of these genes. Increased lipid concentrations may be useful, for example, in the generation of biofuels. Decreased lipid concentration may be useful in the treatment of diseases characterized by excessive lipid storage. In addition, the invention provides methods of identifying markers of diseases characterized by excessive lipid storage.
Public/Granted literature
- US20100021912A1 Methods of Modulating Lipid Concentrations in Eukaryotic Cells Public/Granted day:2010-01-28
Information query
IPC分类:
