Invention Grant
- Patent Title: Tertiary amine substituted peptides useful as inhibitors of HCV replication
- Patent Title (中): 可用作HCV复制抑制剂的叔胺取代肽
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Application No.: US12597380Application Date: 2008-02-26
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Publication No.: US08435984B2Publication Date: 2013-05-07
- Inventor: Atul Agarwal , Xiangzhu Wang , Dawei Chen , Suoming Zhang , Avinash Phadke
- Applicant: Atul Agarwal , Xiangzhu Wang , Dawei Chen , Suoming Zhang , Avinash Phadke
- Applicant Address: US CT New Haven
- Assignee: Achillion Pharmaceuticals, Inc.
- Current Assignee: Achillion Pharmaceuticals, Inc.
- Current Assignee Address: US CT New Haven
- Agency: Cantor Colburn LLP
- International Application: PCT/US2008/002524 WO 20080226
- International Announcement: WO2008/106130 WO 20080904
- Main IPC: C07D401/00
- IPC: C07D401/00 ; C07D405/00 ; C07D403/00 ; C07D217/00 ; A01N43/40 ; A61K31/445 ; A61K31/55
Abstract:
The present invention provides tertiary amine substituted peptides of Formula (I) useful as inhibitors of HCV replication. The variables R and R1-R12 in Formula I are described herein. The invention also includes methods for preparing such compounds. The present invention further includes pharmaceutical compositions containing tertiary amine substituted peptides and methods for using such compounds, including methods for using the compounds to treat hepatitis C infection.
Public/Granted literature
- US20100292219A1 TERTIARY AMINE SUBSTITUTED PEPTIDES USEFUL AS INHIBITORS OF HCV REPLICATION Public/Granted day:2010-11-18
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