Invention Grant
- Patent Title: Dihydropyrimidone amides as P2X7 modulators
- Patent Title (中): 二氢嘧啶酮酰胺作为P2X7调节剂
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Application No.: US12847129Application Date: 2010-07-30
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Publication No.: US08435990B2Publication Date: 2013-05-07
- Inventor: Christine E. Brotherton-Pleiss , Joan Marie Caroon , Francisco Javier Lopez-Tapia , Keith Adrian Murray Walker
- Applicant: Christine E. Brotherton-Pleiss , Joan Marie Caroon , Francisco Javier Lopez-Tapia , Keith Adrian Murray Walker
- Applicant Address: US CA Palo Alto
- Assignee: Roche Palo Alto LLC
- Current Assignee: Roche Palo Alto LLC
- Current Assignee Address: US CA Palo Alto
- Agent Robert C. Hall
- Main IPC: C07D239/22
- IPC: C07D239/22 ; C07D403/12 ; A61K31/513
Abstract:
Compounds of the formula I: or pharmaceutically acceptable salts thereof, wherein m, n, R1, R2, R3, R4, R5, Ra and Rb are as defined herein. Also disclosed are methods of making the compounds and using the compounds for treatment of diseases associated with the P2X7 purinergic receptor.
Public/Granted literature
- US20110028502A1 DIHYDROPYRIMIDONE AMIDES AS P2X7 MODULATORS Public/Granted day:2011-02-03
Information query
