Invention Grant
- Patent Title: Prodrug of triazolone compound
- Patent Title (中): 三唑酮化合物的前药
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Application No.: US13695665Application Date: 2011-05-18
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Publication No.: US08436009B2Publication Date: 2013-05-07
- Inventor: Richard Clark , Fumiyoshi Matsuura , Masanobu Shinoda , Shinsuke Hirota , Kazunobu Kira , Hiroshi Azuma , Atsushi Takemura , So Yasui , Kazutomi Kusano , Masaki Mikamoto , Takao Omae
- Applicant: Richard Clark , Fumiyoshi Matsuura , Masanobu Shinoda , Shinsuke Hirota , Kazunobu Kira , Hiroshi Azuma , Atsushi Takemura , So Yasui , Kazutomi Kusano , Masaki Mikamoto , Takao Omae
- Applicant Address: JP Tokyo
- Assignee: Eisai R&D Management Co., Ltd.
- Current Assignee: Eisai R&D Management Co., Ltd.
- Current Assignee Address: JP Tokyo
- Agency: Fish & Richardson P.C.
- International Application: PCT/JP2011/061919 WO 20110518
- International Announcement: WO2011/145747 WO 20111124
- Main IPC: A61K31/506
- IPC: A61K31/506 ; C07D239/42
Abstract:
By oral administration of a compound represented by the following Formula (I): the blood level of Compound (IV): which has an excellent inhibitory action against blood coagulation factor VIIa and the anticoagulant action, reaches a level sufficient for expression of its pharmacological actions. Therefore, the compound of the present invention is useful as a therapeutic and/or prophylactic agent for diseases caused by thrombus formation.
Public/Granted literature
- US20130053563A1 PRODRUG OF TRIAZOLONE COMPOUND Public/Granted day:2013-02-28
Information query
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