Invention Grant
US08436014B2 Solid forms of N-(4-(7-azabicyclo[2.2.1]heptan-7-yl)-2-(trifluorormethyl)phenyl)-4-oxo-5-(trifluoromethyl)-1,4-dihyroquinoline-3-carboxamide
有权
固体形式的N-（4-（7-氮杂双环[2.2.1]庚-7-基）-2-（三氟甲基）苯基）-4-氧代-5-（三氟甲基）-1,4-二喹啉-3- 甲酰胺
![Solid forms of N-(4-(7-azabicyclo[2.2.1]heptan-7-yl)-2-(trifluorormethyl)phenyl)-4-oxo-5-(trifluoromethyl)-1,4-dihyroquinoline-3-carboxamide](/docs/US/2013-05-07/US08436014B2/abs.jpg.600x600.jpg)
- Patent Title: Solid forms of N-(4-(7-azabicyclo[2.2.1]heptan-7-yl)-2-(trifluorormethyl)phenyl)-4-oxo-5-(trifluoromethyl)-1,4-dihyroquinoline-3-carboxamide
- Patent Title (中): 固体形式的N-（4-（7-氮杂双环[2.2.1]庚-7-基）-2-（三氟甲基）苯基）-4-氧代-5-（三氟甲基）-1,4-二喹啉-3- 甲酰胺
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Application No.: US12605266Application Date: 2009-10-23
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Publication No.: US08436014B2Publication Date: 2013-05-07
- Inventor: Beili Zhang , Mariusz Krawiec , Martyn Botfield , Peter D. J. Grootenhuis , Fredrick Van Goor
- Applicant: Beili Zhang , Mariusz Krawiec , Martyn Botfield , Peter D. J. Grootenhuis , Fredrick Van Goor
- Applicant Address: US MA Cambridge
- Assignee: Vertex Pharmaceutical Incorporated
- Current Assignee: Vertex Pharmaceutical Incorporated
- Current Assignee Address: US MA Cambridge
- Agency: Honigman Miller Schwartz and Cohn LLP
- Agent Christopher C. Forbes; Jonathan P. O'Brien
- Main IPC: A61K31/47
- IPC: A61K31/47 ; C07D215/00
![Solid forms of N-(4-(7-azabicyclo[2.2.1]heptan-7-yl)-2-(trifluorormethyl)phenyl)-4-oxo-5-(trifluoromethyl)-1,4-dihyroquinoline-3-carboxamide](/abs-image/US/2013/05/07/US08436014B2/abs.jpg.150x150.jpg)
Abstract:
The present invention relates to solid state forms, for example, crystalline forms of N-(4-(7-azabicyclo[2.2.1]heptan-7-yl)-2-(trifluoromethyl)phenyl)-4-oxo-5-(trifluoromethyl)-1,4-dihydroquinoline-3-carboxamide, pharmaceutical compositions thereof, and methods therewith.
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