Invention Grant
US08436139B2 Peptide-based immunization therapy for treatment of atherosclerosis
有权
基于肽的免疫治疗动脉粥样硬化的治疗
- Patent Title: Peptide-based immunization therapy for treatment of atherosclerosis
- Patent Title (中): 基于肽的免疫治疗动脉粥样硬化的治疗
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Application No.: US11373682Application Date: 2006-03-10
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Publication No.: US08436139B2Publication Date: 2013-05-07
- Inventor: Göran K. Hansson
- Applicant: Göran K. Hansson
- Applicant Address: US CA Torrance
- Assignee: CardioVax, LLC
- Current Assignee: CardioVax, LLC
- Current Assignee Address: US CA Torrance
- Agency: K&L Gates LLP
- Agent Louis C. Cullman; Michelle Glasky Bergman
- Priority: SE0302422 20030911
- Main IPC: C07K14/00
- IPC: C07K14/00
Abstract:
The present invention relates to a fragment of apolipoprotein B, for immunization for prophylactic or therapeutic treatment of mammals, including humans, against ischemic cardiovascular diseases, in particular myocardial infarction or stroke, as well as diagnosing the presence or absence of antibodies related to increased or decreased risk of developing ischemic cardiovascular diseases including stroke, using said peptide in an assay, pharmaceutical compositions comprising the peptide. The invention further encompasses a particular peptide sequence aggravating disease, which sequence then can be used for diagnostic assays.
Public/Granted literature
- US20060233817A1 Peptide-based immunization therapy for treatment of atherosclerosis Public/Granted day:2006-10-19
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