Invention Grant
- Patent Title: Natriuretic peptide-mediated imaging of atherosclerotic plaque
- Patent Title (中): 利钠肽介导的动脉粥样硬化斑块成像
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Application No.: US12454810Application Date: 2009-05-22
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Publication No.: US08436140B2Publication Date: 2013-05-07
- Inventor: Pamela K. Woodard , Michael J. Welch , Geoffrey E. Woodard , Rafaella Rossin
- Applicant: Pamela K. Woodard , Michael J. Welch , Geoffrey E. Woodard , Rafaella Rossin
- Applicant Address: US MO Saint Louis
- Assignee: Washington University
- Current Assignee: Washington University
- Current Assignee Address: US MO Saint Louis
- Agency: Zackson Law LLC
- Agent Saul L. Zackson
- Main IPC: C07K9/00
- IPC: C07K9/00
Abstract:
Tracers comprising an oligopeptide comprising a fragment of a natriuretic peptide, wherein the fragment comprises the sequence Arg-Ile-Asp-Arg-Ile (SEQ ID NO.: 1), and a signaling moiety, are disclosed. Further disclosed are methods of imaging atherosclerotic plaque by PET scanning or MRI using a tracer.
Public/Granted literature
- US20100021381A1 Natriuretic peptide-mediated imaging of atherosclerotic plaque Public/Granted day:2010-01-28
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