Invention Grant
- Patent Title: Processing of recombinant human G-CSF precursor
- Patent Title (中): 重组人G-CSF前体的加工
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Application No.: US13122487Application Date: 2009-10-02
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Publication No.: US08436142B2Publication Date: 2013-05-07
- Inventor: Carola Schröder , Elisabeth Casademunt , Peter Söhlemann , Michael Lehnerer
- Applicant: Carola Schröder , Elisabeth Casademunt , Peter Söhlemann , Michael Lehnerer
- Applicant Address: CH Lachen
- Assignee: Octapharma AG
- Current Assignee: Octapharma AG
- Current Assignee Address: CH Lachen
- Agency: Venable LLP
- Agent Nancy J. Axelrod; Michael A. Gollin
- Priority: EP08165758 20081002
- International Application: PCT/EP2009/062843 WO 20091002
- International Announcement: WO2010/037855 WO 20100408
- Main IPC: A61K38/00
- IPC: A61K38/00 ; C07H21/04 ; C12N15/00
Abstract:
A G-CSF precursor comprising a signal peptide and a G-CSF peptide, wherein the signal peptide has the sequence of the human wild-type signal peptide of the human G-CSF/b molecule with at least one of the following mutations: deletion of Glu29, insertion of Glu26, substitution Lys11Leu, substitution His21Phe, and substitution Gln28Leu.
Public/Granted literature
- US20110294989A1 PROCESSING OF RECOMBINANT HUMAN G-CSF Public/Granted day:2011-12-01
Information query
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