Invention Grant
- Patent Title: Serine protease derivatives and uses in the prevention or the treatment of blood coagulation disorders
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Application No.: US13139367Application Date: 2009-12-21
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Publication No.: US08436144B2Publication Date: 2013-05-07
- Inventor: Olivier Christophe , Cecile Denis , Ghislaine Cherel , Paul Gueguen
- Applicant: Olivier Christophe , Cecile Denis , Ghislaine Cherel , Paul Gueguen
- Applicant Address: FR Paris
- Assignee: Institut National de la Sante et de la Recherche Medicale (INSERM)
- Current Assignee: Institut National de la Sante et de la Recherche Medicale (INSERM)
- Current Assignee Address: FR Paris
- Agency: Whitham Curtis Christofferson & Cook, PC
- Priority: EP08305990 20081219; EP09305349 20090423
- International Application: PCT/EP2009/067632 WO 20091221
- International Announcement: WO2010/070137 WO 20100624
- Main IPC: A61K35/14
- IPC: A61K35/14 ; C07H21/04
Abstract:
The present invention relates to chimeric derivatives of serine protease zymogen containing the activation peptide of factor X or a fragment thereof for improving the half-life of said derivatives. Preferably, said chimeric derivatives are protein C and factor X derivatives. The invention also relates to said derivatives for the prevention or treatment of blood coagulation disorders.
Public/Granted literature
- US20110293597A1 SERINE PROTEASE DERIVATIVES AND USES IN THE PREVENTION OR THE TREATMENT OF BLOOD COAGULATION DISORDERS Public/Granted day:2011-12-01
Information query
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