Invention Grant
US08436155B2 7,2″-dehydrate puerarin and its salts, preparation method and use thereof
有权
7,2“ - 脱水葛根素及其盐，其制备方法和用途
- Patent Title: 7,2″-dehydrate puerarin and its salts, preparation method and use thereof
- Patent Title (中): 7,2“ - 脱水葛根素及其盐，其制备方法和用途
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Application No.: US13177575Application Date: 2011-07-07
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Publication No.: US08436155B2Publication Date: 2013-05-07
- Inventor: Hongxiang Lou , Jian Gao , Xia Xue
- Applicant: Hongxiang Lou , Jian Gao , Xia Xue
- Applicant Address: CN Jinan
- Assignee: Shandong University
- Current Assignee: Shandong University
- Current Assignee Address: CN Jinan
- Agency: Matthias Scholl P.C.
- Agent Matthias Scholl
- Priority: CN201010159299 20100429
- Main IPC: C07H15/00
- IPC: C07H15/00 ; C07H17/00 ; C07H17/02 ; C07H15/04 ; C07H1/00 ; C07H3/00
Abstract:
A 7,2″-dehydrate puerarin represented by formula (I) and salt derivatives thereof. The compounds are prepared from puerarin by intramolecular mitsunobu reaction. They are capable of shortening arrhythmia duration and prolonging coagulation time. They can be prepared into oral formulations or injections for treatment of cardiovascular and cerebrovascular diseases including arrhythmia, coronary heart disease, angina pectoris, myocardial infarction, and cerebral infarction.
Public/Granted literature
- US20110269701A1 7,2''-DEHYDRATE PUERARIN AND ITS SALTS, PREPARATION METHOD AND USE THEREOF Public/Granted day:2011-11-03
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