Invention Grant
- Patent Title: Method for the production of sucralose
- Patent Title (中): 生产三氯蔗糖的方法
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Application No.: US12409951Application Date: 2009-03-24
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Publication No.: US08436157B2Publication Date: 2013-05-07
- Inventor: James Edwin Wiley, Jr. , Duane A. Leinhos , David A. Dentel , John Kerr
- Applicant: James Edwin Wiley, Jr. , Duane A. Leinhos , David A. Dentel , John Kerr
- Applicant Address: GB London
- Assignee: Tate & Lyle Technology Limited
- Current Assignee: Tate & Lyle Technology Limited
- Current Assignee Address: GB London
- Agency: RatnerPrestia
- Main IPC: C07H1/00
- IPC: C07H1/00

Abstract:
The present invention provides a method for producing sucralose from a feed stream including a sucrose-6-acylate in a reaction vehicle. The method includes: (i) reacting the sucrose-6-acylate with a chlorinating agent in order to chlorinate the 4, 1′ and 6′ positions of the sucrose-6-acylate; (ii) quenching the product stream of (i) with an aqueous solution of a base to provide a sucralose-6-acylate and the chloride salt of said base, wherein the concentration of the aqueous solution of the base is sufficiently high such that at least a portion of the chloride salt of the base is formed as a precipitate; (iii) either: deacylating the sucralose-6-acylate by treating the product stream of (ii) with a base and thereafter removing precipitated salt to provide a product stream including sucralose; or: removing precipitated salt from the product stream of (ii) and thereafter deacylating the sucralose-6-acylate by treating with a base to provide a product stream including sucralose; and (iv) isolating sucralose from the product stream of (iii).
Public/Granted literature
- US20090247737A1 METHOD FOR THE PRODUCTION OF SUCRALOSE Public/Granted day:2009-10-01
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