The present disclosure includes systems and techniques relating to low power current-voltage mixed ADC architecture. In some implementations, an apparatus includes sample and hold circuitry, at least one ADC module configured to generate a first digital output based on a first analog input provided to the sample and hold circuitry, and current generation circuitry configured to modulate an analog output of the sample and hold circuitry to generate a residue output corresponding to the first analog input absent at least a portion corresponding to the first digital output, and to provide the residue output as a second analog input to further circuitry to generate a second digital output.