Invention Grant
US08440419B2 Method and kit for quantitatively determining small, dense LDL cholesterol
有权
定量测定小而密LDL胆固醇的方法和试剂盒
- Patent Title: Method and kit for quantitatively determining small, dense LDL cholesterol
- Patent Title (中): 定量测定小而密LDL胆固醇的方法和试剂盒
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Application No.: US12682240Application Date: 2008-10-10
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Publication No.: US08440419B2Publication Date: 2013-05-14
- Inventor: Yasuki Itoh , Miki Fujimura
- Applicant: Yasuki Itoh , Miki Fujimura
- Applicant Address: JP Tokyo
- Assignee: Denka Seiken Co., Ltd.
- Current Assignee: Denka Seiken Co., Ltd.
- Current Assignee Address: JP Tokyo
- Agency: Foley & Lardner LLP
- Priority: JP2007-264908 20071010
- International Application: PCT/JP2008/068489 WO 20081010
- International Announcement: WO2009/048143 WO 20090416
- Main IPC: C12Q1/60
- IPC: C12Q1/60
Abstract:
A method for fractional measurement of small, dense LDL, which is adaptable for an autoanalyzer, and a reagent for measurement, are provided, making it possible to conduct rapid and convenient analysis with good sensitivity without pretreatment of a specimen. The method for quantitatively determining small, dense LDL cholesterol in a sample comprises the steps of: (1) eliminating cholesterol in LDL other than small, dense LDL in the presence of phospholipase; and (2) quantitatively determining cholesterol in lipoproteins remaining in step (1) above.
Public/Granted literature
- US20100255516A1 METHOD AND KIT FOR QUANTITATIVELY DETERMINING SMALL, DENSE LDL CHOLESTEROL Public/Granted day:2010-10-07
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