Invention Grant
US08440611B2 Analogues of neuropeptide Y having at least one synthetic amino acid substitution
有权
具有至少一个合成氨基酸取代的神经肽Y的类似物
- Patent Title: Analogues of neuropeptide Y having at least one synthetic amino acid substitution
- Patent Title (中): 具有至少一个合成氨基酸取代的神经肽Y的类似物
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Application No.: US13202030Application Date: 2010-02-19
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Publication No.: US08440611B2Publication Date: 2013-05-14
- Inventor: Zheng Xin Dong , Kevin Zhou , Daniel B. Deoliveira
- Applicant: Zheng Xin Dong , Kevin Zhou , Daniel B. Deoliveira
- Applicant Address: FR Boulogne
- Assignee: Ipsen Pharma S.A.S.
- Current Assignee: Ipsen Pharma S.A.S.
- Current Assignee Address: FR Boulogne
- Agent Tony K. Uhm
- International Application: PCT/US2010/000491 WO 20100219
- International Announcement: WO2010/096186 WO 20100826
- Main IPC: A61K38/00
- IPC: A61K38/00
Abstract:
The present invention relates to novel analogues of neuropeptide Y, pharmaceutical compositions containing the same, pharmaceutical formulations containing the same, and method of treating diseases or conditions mediated by neuropeptide Y-receptor binding. More particularly, the present invention relates to novel analogues of neuropeptide Y having at least one unnatural amino acid substitution, such as 4Hyp at position 34 , that selectively bind to the neuropeptide Y1 receptor subtype compared to the neuropeptide Y2 receptor subtype.
Public/Granted literature
- US20120040885A1 Analogues of Neuropeptide Y Having At Least One Synthetic Amino Acid Substitution Public/Granted day:2012-02-16
Information query
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