Invention Grant
- Patent Title: Combination compositions for reducing intraocular pressure
- Patent Title (中): 用于降低眼内压的组合组合物
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Application No.: US13051633Application Date: 2011-03-18
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Publication No.: US08440639B2Publication Date: 2013-05-14
- Inventor: Norman N. Kim , William K. McVicar , Thomas G. McCauley
- Applicant: Norman N. Kim , William K. McVicar , Thomas G. McCauley
- Applicant Address: US MA Lexington
- Assignee: Inotek Pharmaceuticals Corporation
- Current Assignee: Inotek Pharmaceuticals Corporation
- Current Assignee Address: US MA Lexington
- Agency: Nelson Mullins Riley & Scarborough LLP
- Agent Jane E. Remillard, Esq.; Cynthia L. Kanik
- Main IPC: A61K31/70
- IPC: A61K31/70 ; A61K31/54 ; A61K31/41 ; A61K31/38 ; A01N43/18 ; C07H19/167 ; C07H19/173 ; C07D285/12 ; C07D285/14 ; C07D417/00 ; C07D513/00 ; C07D327/10 ; C07D339/02 ; C07D341/00 ; C07D409/00 ; C07D411/00 ; C07D495/00 ; C07D497/00 ; C07D285/22 ; C07D285/26
Abstract:
Provided herein is a pharmaceutical composition or a kit comprising a combination of a carbonic anhydrase inhibitor analog and an adenosine A1 receptor agonist. Also provided herein is a method of reducing intraocular pressure (IOP) in a subject using such a combination or kit. In a particular embodiment, provided herein is a combination of dorzolamide marketed under the brand Trusopt™ and Compound A.
Public/Granted literature
- US20110245193A1 COMBINATION COMPOSITIONS FOR REDUCING INTRAOCULAR PRESSURE Public/Granted day:2011-10-06
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