Invention Grant
- Patent Title: Pyridazinone compounds and P2X7 receptor inhibitors
- Patent Title (中): 哒嗪酮化合物和P2X7受体抑制剂
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Application No.: US12680689Application Date: 2008-10-30
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Publication No.: US08440666B2Publication Date: 2013-05-14
- Inventor: Yukihiro Shigeta , Yutaka Hirokawa , Hiroshi Nagai , Kei Nagae , Tsuneo Watanabe , Megumi Io , Yusuke Shintani , Junji Kamon , Masato Horikawa , Kazuya Takeuchi
- Applicant: Yukihiro Shigeta , Yutaka Hirokawa , Hiroshi Nagai , Kei Nagae , Tsuneo Watanabe , Megumi Io , Yusuke Shintani , Junji Kamon , Masato Horikawa , Kazuya Takeuchi
- Applicant Address: JP Tokyo
- Assignee: Nissan Chemical Industries, Ltd.
- Current Assignee: Nissan Chemical Industries, Ltd.
- Current Assignee Address: JP Tokyo
- Agency: Oblon, Spivak, McClelland, Maier & Neustadt, L.L.P.
- Priority: JP2007-284189 20071031; JP2008-229921 20080908
- International Application: PCT/JP2008/070261 WO 20081030
- International Announcement: WO2009/057827 WO 20090507
- Main IPC: C07D239/70
- IPC: C07D239/70 ; C07D213/16 ; C07D237/08 ; C07D471/04 ; C07D239/28 ; C07D413/04 ; A61K31/517 ; A61K31/4409 ; A61K31/50 ; A61K31/437 ; A61K31/4965 ; A61P25/04
Abstract:
Novel pyridazinone compounds of formula (I), which inhibit the purinergic P2X7 receptor and are useful for prevention, therapy and improvement of inflammatory and immunological diseases.
Public/Granted literature
- US20100286390A1 PYRIDAZINONE COMPOUNDS AND P2X7 RECEPTOR INHIBITORS Public/Granted day:2010-11-11
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