Invention Grant
US08440691B2 Tetrahydroquinolinyl compounds that inhibit vanilloid receptor subtype 1 (VR1) receptor and uses thereof
有权
抑制香草素受体亚型1（VR1）受体的四氢喹啉基化合物及其用途
- Patent Title: Tetrahydroquinolinyl compounds that inhibit vanilloid receptor subtype 1 (VR1) receptor and uses thereof
- Patent Title (中): 抑制香草素受体亚型1（VR1）受体的四氢喹啉基化合物及其用途
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Application No.: US12875839Application Date: 2010-09-03
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Publication No.: US08440691B2Publication Date: 2013-05-14
- Inventor: Arthur Gomtsyan , Erol K. Bayburt , Robert G. Schmidt, Jr. , Chih-Hung Lee , Brian S. Brown , Tammie K. Jinkerson , John R. Koenig , Jerome F. Daanen , Steven P. Latshaw
- Applicant: Arthur Gomtsyan , Erol K. Bayburt , Robert G. Schmidt, Jr. , Chih-Hung Lee , Brian S. Brown , Tammie K. Jinkerson , John R. Koenig , Jerome F. Daanen , Steven P. Latshaw
- Applicant Address: US IL North Chicago
- Assignee: AbbVie Inc.
- Current Assignee: AbbVie Inc.
- Current Assignee Address: US IL North Chicago
- Main IPC: A61K31/47
- IPC: A61K31/47 ; A61K31/445 ; A61K31/415 ; C07D217/00 ; C07D215/00 ; C07D211/00 ; C07D231/56
Abstract:
Compounds that are antagonists of the VR1 receptor, having formula (I) or a pharmaceutically acceptable salt, prodrug, or salt of a prodrug thereof, wherein A1, A2, A3, A4, R7, R8, R9, X, Y, Z, L, n, and m, are as defined herein, and are useful in disorders prevented or ameliorated by inhibiting the VR1 receptor.
Public/Granted literature
- US20110152250A1 CHROMANYLUREA COMPOUNDS THAT INHIBIT VANILLOID RECEPTOR SUBTYPE 1 (VR1) RECEPTOR AND USES THEREOF Public/Granted day:2011-06-23
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