Invention Grant
US08440694B2 Quinoline compounds suitable for treating disorders that respond to modulation of the serotonin-5-HT6 receptor
有权
喹啉化合物适用于治疗对血清素-5-HT6受体调节作用的疾病
- Patent Title: Quinoline compounds suitable for treating disorders that respond to modulation of the serotonin-5-HT6 receptor
- Patent Title (中): 喹啉化合物适用于治疗对血清素-5-HT6受体调节作用的疾病
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Application No.: US13613344Application Date: 2012-09-13
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Publication No.: US08440694B2Publication Date: 2013-05-14
- Inventor: Sean Colm Turner , Wilfried Braje , Andreas Haupt , Udo Lange , Karla Drescher , Karsten Wicke , Liliane Unger , Mario Mezler , Matthias Mayrer , Wolfgang Wernet
- Applicant: Sean Colm Turner , Wilfried Braje , Andreas Haupt , Udo Lange , Karla Drescher , Karsten Wicke , Liliane Unger , Mario Mezler , Matthias Mayrer , Andrea Hager-Wernet
- Applicant Address: DE Wiesbaden
- Assignee: Abbott GmbH & Co. KG
- Current Assignee: Abbott GmbH & Co. KG
- Current Assignee Address: DE Wiesbaden
- Agency: Michael Best & Friedrich LLP
- Agent Lisa V. Mueller
- Priority: EP07113962 20070807
- Main IPC: A61K31/47
- IPC: A61K31/47 ; A61P3/04 ; A61P25/00 ; A61P25/18 ; A61P25/28 ; A61P25/30 ; C07D215/36
Abstract:
The present invention relates to novel quinoline compounds of the formula (I) and to the salts thereof. The compounds possess valuable therapeutic properties and are particularly suitable, for treating diseases that respond to modulation of the serotonin 5-HT6 receptor. In formula (I) R is a moiety of the formula (R) wherein * indicates the binding site to the quinolinyl radical and wherein A, B, X′, Y, Q, R1, R2, R3, R4, R5, m, n, p, q, Ra, Rb, X and Ar are as defined in claim 1.
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