Invention Grant
- Patent Title: RNA antagonists targeting Hsp27
- Patent Title (中): 靶向Hsp27的RNA拮抗剂
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Application No.: US13000278Application Date: 2009-07-01
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Publication No.: US08440809B2Publication Date: 2013-05-14
- Inventor: Jesper Worm
- Applicant: Jesper Worm
- Applicant Address: DK Hoersholm
- Assignee: Santaris Pharma A/S
- Current Assignee: Santaris Pharma A/S
- Current Assignee Address: DK Hoersholm
- Agency: Fish & Richardson P.C.
- Priority: EP08104612 20080702
- International Application: PCT/IB2009/052860 WO 20090701
- International Announcement: WO2010/001349 WO 20100107
- Main IPC: C07H21/04
- IPC: C07H21/04 ; C12N15/11 ; C12Q1/68
Abstract:
The present invention relates to oligomer compounds (oligomers), which target Hsp27 mRNA in a cell, leading to reduced expression of Hsp27. Reduction of Hsp27 expression is beneficial for the treatment of certain medical disorders, such as cancer. The invention provides therapeutic compositions comprising oligomers and methods for modulating the expression of Hsp27 using the oligomers, including methods of treatment.
Public/Granted literature
- US20110144185A1 RNA ANTAGONISTS TARGETING HSP27 Public/Granted day:2011-06-16
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