Invention Grant
US08440860B2 Process for manufacturing N, N-dialkyl lactamide 有权
制备N,N-二烷基乳酰胺的方法

  • Patent Title: Process for manufacturing N, N-dialkyl lactamide
  • Patent Title (中): 制备N,N-二烷基乳酰胺的方法
  • Application No.: US13121275
    Application Date: 2009-09-30
  • Publication No.: US08440860B2
    Publication Date: 2013-05-14
  • Inventor: Jan Van Krieken
  • Applicant: Jan Van Krieken
  • Applicant Address: NL Gorinchem
  • Assignee: Purac Biochem BV
  • Current Assignee: Purac Biochem BV
  • Current Assignee Address: NL Gorinchem
  • Agency: Oliff & Berridge, PLC
  • Priority: EP08165639 20081001
  • International Application: PCT/EP2009/062683 WO 20090930
  • International Announcement: WO2010/037776 WO 20100408
  • Main IPC: C07C231/02
  • IPC: C07C231/02
Process for manufacturing N, N-dialkyl lactamide
Abstract:
A process for manufacturing dialkyl lactamide including reacting lactide and dialkylamine selected from one or more of dimethylamine, diethylamine, and methylethylamine to form a reaction mixture which includes dialkyl lactamide selected from N,N-dimethyl lactamide, N,N-diethyl lactamide, and N,N-methylethyl lactamide, N,N-dialkyl lactoyl lactamide, and dialkylamine, subjecting the reaction mixture to a separation step to form a product stream including N,N-dialkyl lactamide, a first recycle stream including dialkylamine and a second recycle stream including N,N-dialkyl lactoyl lactamide, feeding the recycle streams to the reaction step, and isolating the product stream. The process allows the manufacture of N,N-dimethyl lactamide, N,N-diethyl lactamide, and N,N-methylethyl lactamide on a commercial scale.
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