A high-security enclosure includes a base, a cover and a lock system. The lock system includes a base portion and a cover portion. The lock system base portion includes one or more fixed lock bars. The lock system cover portion includes one or more movable lock bars. Each movable lock bar is generally perpendicular to, and arranged to engage, one of the fixed lock bars. The lock system cover portion further includes a lock bar retraction assembly coupled to the one or more movable lock bars for retracting the movable lock bar(s) substantially simultaneously out of engagement with the fixed lock bar(s). A security drive mechanism is coupled to the lock bar retraction assembly to drive the lock system.