A LED module with fast disassembly function is capable of being disassembled from a hole of a substrate by a tool and includes a lamp base, a LED and fasteners. The lamp base has tabs extending outwards. Each of the tabs is provided with a through-hole corresponding to the hole. The tab is formed with an inclined surface at the periphery of the through-hole. The LED is fixed on the lamp base. Each of the fasteners has a cap. The fastener is disposed through the hole and the through-hole to be fixed thereto. A notch is formed between the cap and the inclined surface. The tool is disposed in the notch to thereby disassemble the fastener from the hole and the through-hole. With this arrangement, the damaged LED can be detached from the substrate rapidly without replacing the whole LED module, thereby reducing the time and cost for maintenance.