Invention Grant
- Patent Title: Anti-misuse microparticulate oral pharmaceutical form
- Patent Title (中): 反滥用微粒口服药物形式
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Application No.: US12638739Application Date: 2009-12-15
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Publication No.: US08445023B2Publication Date: 2013-05-21
- Inventor: Florence Guimberteau , Frederic Dargelas
- Applicant: Florence Guimberteau , Frederic Dargelas
- Applicant Address: FR
- Assignee: Flamel Technologies
- Current Assignee: Flamel Technologies
- Current Assignee Address: FR
- Agency: Patton Boggs LLP
- Priority: FR0553437 20051110
- Main IPC: A61K9/16
- IPC: A61K9/16

Abstract:
The present invention relates to solid microparticulate oral pharmaceutical forms whose composition and structure make it possible to avoid misuse of the pharmaceutical active principle (AP) they contain.The object of the present invention is to prevent solid oral drugs from being misappropriated for any use other than the therapeutic use(s) officially approved by the competent public health authorities. In other words, the object is to avoid the voluntary or involuntary misuse of solid oral drugs.The invention relates to a solid oral pharmaceutical form which is characterized in that it contains anti-misuse means, in that at least part of the AP it comprises is contained in coated microparticles for modified release of the AP, and in that the coated microparticles of AP have a coating layer (Ra) which assures the modified release of the AP and simultaneously imparts crushing resistance to the coated microparticles of AP so as to avoid misuse.
Public/Granted literature
- US20100092553A1 ANTI-MISUSE MICROPARTICULATE ORAL PHARMACEUTICAL FORM Public/Granted day:2010-04-15
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