Invention Grant
- Patent Title: Plant derived antibiotic peptide rich in glycine
- Patent Title (中): 植物来源的富含甘氨酸的抗生素肽
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Application No.: US12521716Application Date: 2008-01-02
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Publication No.: US08445428B2Publication Date: 2013-05-21
- Inventor: Octavio Franco , Patricia Barbosa Pelegrini , Carlos Bloch Junior , Luciano Paulino Silva
- Applicant: Octavio Franco , Patricia Barbosa Pelegrini , Carlos Bloch Junior , Luciano Paulino Silva
- Applicant Address: BR Taguantinga-DF BR Brasilia-DF
- Assignee: Uniao Brasiliense de Educacao e Cultura—UBEC,Empresa Brasileira de Pesquisa Agropercuaria—EMBRAPA
- Current Assignee: Uniao Brasiliense de Educacao e Cultura—UBEC,Empresa Brasileira de Pesquisa Agropercuaria—EMBRAPA
- Current Assignee Address: BR Taguantinga-DF BR Brasilia-DF
- Agency: Arent Fox LLP
- Priority: BR0605658 20061229
- International Application: PCT/BR2008/000001 WO 20080102
- International Announcement: WO2008/080208 WO 20080710
- Main IPC: A61K38/00
- IPC: A61K38/00
Abstract:
The present invention relates to a novel peptide extracted from guava (Psidium guajava) seeds, that provides bactericide activity, Preferentially against Gram-negative bacteria which are known to cause urinary, hospital, and intestinal tract infections (Proteus sp. And Klebsiella sp.). The peptide, that has the amino acid sequence RESPSSRMEC YEQAERYGYG GYGGGRYGGG YGSGRGQPVG QGVERSHDDN RNQPR, belongs to the class of glycine rich proteins and has approximately 5 kDa of molecular weight. The invention also relates to antibiotic compositions for human, veterinary and plant treatments. Alternatively, the peptide, or a functionally similar derivative, subjects of the present invention, can be used for transforming organisms aiming pathogen resistance, other adaptive advantages, as well as various properties, specially for plants and animals.
Public/Granted literature
- US20110190197A1 PLANT DERIVED ANTIBIOTIC PEPTIDE RICH IN GLYCINE Public/Granted day:2011-08-04
Information query
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