Invention Grant
- Patent Title: Dimeric IAP inhibitors
- Patent Title (中): 二聚体IAP抑制剂
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Application No.: US13033463Application Date: 2011-02-23
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Publication No.: US08445440B2Publication Date: 2013-05-21
- Inventor: Christopher Straub , Zhuoliang Chen , Mark Palermo
- Applicant: Christopher Straub , Zhuoliang Chen , Mark Palermo
- Applicant Address: CH Basel
- Assignee: Novartis AG
- Current Assignee: Novartis AG
- Current Assignee Address: CH Basel
- Agent Arlene K. Musser
- Main IPC: A61K38/05
- IPC: A61K38/05 ; A61K38/06 ; C07K5/037
Abstract:
The present invention provides compounds of formula M-L-M′ (where M and M′ are each independently a monomeric moiety of Formula (I) and L is a linker). The dimeric compounds have been found to be effective in promoting apoptosis in rapidly dividing cells.
Public/Granted literature
- US20110206690A1 DIMERIC IAP INHIBITORS Public/Granted day:2011-08-25
Information query
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