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US08445480B2 CETP inhibitors derived from benzoxazole arylamides 有权
衍生自苯并恶唑芳酰胺的CETP抑制剂

CETP inhibitors derived from benzoxazole arylamides
Abstract:
Compounds having the structure of Formula I1 including pharmaceutically acceptable salts of the compounds, are potent CETP (cholesterol ester transfer protein) inhibitors, and are useful for raising HDL-cholesterol, reducing LDL-cholesterol, and for treating or preventing atherosclerosis Atherosclerosis and its clinical consequences, coronary heart disease (CHD), stroke and penpheral vascular disease, represent a truly enormous burden to the health care systems of the industrialized world In formula I, A-B is an arylamide moiety.
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