- Patent Title: Thieno- and furo-pyrimidine modulators of the histamine H4 receptor
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Application No.: US13456174Application Date: 2012-04-25
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Publication No.: US08445482B2Publication Date: 2013-05-21
- Inventor: James P. Edwards , Danielle K. Neff , Deborah M. Smith , Jennifer D. Venable
- Applicant: James P. Edwards , Danielle K. Neff , Deborah M. Smith , Jennifer D. Venable
- Applicant Address: BE Beerse
- Assignee: Janssen Pharmaceutica NV
- Current Assignee: Janssen Pharmaceutica NV
- Current Assignee Address: BE Beerse
- Main IPC: C07D243/08
- IPC: C07D243/08 ; C07D491/147 ; A61K31/5513 ; A61K31/5025 ; A61K31/501 ; A61K31/519 ; A61P29/00
Abstract:
Thieno- and furo-pyrimidine compounds are described, which are useful as H4 receptor modulators. Such compounds may be used in pharmaceutical compositions and methods for the modulation of histamine H4 receptor activity and for the treatment of disease states, disorders, and conditions mediated by H4 receptor activity, such as inflammation.
Public/Granted literature
- US20120270855A1 THIENO- AND FURO-PYRIMIDINE MODULATORS OF THE HISTAMINE H4 RECEPTOR Public/Granted day:2012-10-25
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