Invention Grant
- Patent Title: Pyrimidine derivatives as kinase inhibitors
- Patent Title (中): 嘧啶衍生物作为激酶抑制剂
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Application No.: US13000999Application Date: 2009-06-24
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Publication No.: US08445505B2Publication Date: 2013-05-21
- Inventor: Thomas H. Marsilje, III , Wenshuo Lu , Bei Chen , Xiaohui He , Songchun Jiang , Kunyong Yang
- Applicant: Thomas H. Marsilje, III , Wenshuo Lu , Bei Chen , Xiaohui He , Songchun Jiang , Kunyong Yang
- Applicant Address: BM Hamilton
- Assignee: IRM LLC
- Current Assignee: IRM LLC
- Current Assignee Address: BM Hamilton
- Agency: Genomics Institute of the Novartis Research Foundation
- Agent Emily Tongeo Wu
- International Application: PCT/US2009/048509 WO 20090624
- International Announcement: WO2009/158431 WO 20091230
- Main IPC: C07D403/12
- IPC: C07D403/12 ; A61K31/506
Abstract:
The invention provides novel pyrimidine derivatives of formula (I) and pharmaceutical compositions thereof, and methods for using such compounds. For example, the pyrimidine derivatives of the invention may be used to treat, ameliorate or prevent a condition which responds to inhibition of insulin-like growth factor (IGF-IR) or analplastic lymphoma kinase (ALK).
Public/Granted literature
- US20110112096A1 PYRIMIDINE DERIVATIVES AS KINASE INHIBITORS Public/Granted day:2011-05-12
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