Invention Grant
US08445519B2 1-aryl-5-alkyl pyrazole derivative compounds, processes of making and methods of using thereof
有权
1-芳基-5-烷基吡唑衍生物化合物,其制备方法及其使用方法
- Patent Title: 1-aryl-5-alkyl pyrazole derivative compounds, processes of making and methods of using thereof
- Patent Title (中): 1-芳基-5-烷基吡唑衍生物化合物,其制备方法及其使用方法
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Application No.: US12814289Application Date: 2010-06-11
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Publication No.: US08445519B2Publication Date: 2013-05-21
- Inventor: Hyoung Ik Lee , Loïc Patrick Le Hir de Fallois , Philip Reid Timmons , William Glenn Cawthorne, Jr. , Adalberto Perez de Leon
- Applicant: Hyoung Ik Lee , Loïc Patrick Le Hir de Fallois , Philip Reid Timmons , William Glenn Cawthorne, Jr. , Adalberto Perez de Leon
- Applicant Address: FR Paris
- Assignee: Aventis Agriculture
- Current Assignee: Aventis Agriculture
- Current Assignee Address: FR Paris
- Agency: Merial Limited
- Agent Judy Jarecki-Black; John Ezcurra
- Main IPC: A61K31/4439
- IPC: A61K31/4439 ; A61K31/415

Abstract:
Provided are 1-aryl-5-alkyl pyrazole compounds, of formula (I): wherein: R1 is hydrogen, cyano, halogen, R8, formyl, —C(O)R8, —C(O)OR8, —C(O)NR9R10, or —C(S)NH2; R2 is R8 or —S(O)mR11; R3 is methyl, ethyl or C1-C4 haloalkyl; R4, R5 and R7 are independently hydrogen, halogen, alkyl, haloalkyl, cyano or nitro; R6 is halogen, alkyl, haloalkyl, alkoxy, haloalkyloxy, cyano, nitro, —C(O)R12, —S(O)nR12 or SF5; Z is a nitrogen atom or C—R13; R8 is alkyl, haloalkyl, cycloalkyl or halocycloalkyl; R9 is hydrogen, alkyl, haloalkyl or alkoxy; R10 is hydrogen, alkyl, haloalkyl or alkoxy; R11 is alkyl, haloalkyl, alkenyl, haloalkenyl, alkynyl, haloalkynyl or cycloalkyl; R12 is alkyl or haloalkyl; R13 is hydrogen, halogen, cyano, nitro, alkyl, haloalkyl, alkoxy or haloalkoxy; m is 0, 1 or 2; and n is 0, 1 or 2; or a salt thereof, the method of making compounds of formula (I) and the use of these compounds against ectoparasites, endoparasites and pests.
Public/Granted literature
- US20100249194A1 1-ARYL-5-ALKYL PYRAZOLE DERIVATIVE COMPOUNDS, PROCESSES OF MAKING AND METHODS OF USING THEREOF Public/Granted day:2010-09-30
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