Invention Grant
US08445643B2 Anti-IRC85 monoclonal antibody; and composition comprising the same for preventing and treating tuberculosis or enteritis disease; and the use thereof
有权
抗IRC85单克隆抗体; 和包含其的组合物用于预防和治疗结核病或肠炎疾病; 及其用途
- Patent Title: Anti-IRC85 monoclonal antibody; and composition comprising the same for preventing and treating tuberculosis or enteritis disease; and the use thereof
- Patent Title (中): 抗IRC85单克隆抗体; 和包含其的组合物用于预防和治疗结核病或肠炎疾病; 及其用途
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Application No.: US12596747Application Date: 2008-04-24
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Publication No.: US08445643B2Publication Date: 2013-05-21
- Inventor: Byoung Se Kwon
- Applicant: Byoung Se Kwon
- Applicant Address: KR Gyeonggi-do
- Assignee: Bio-Support Co., Ltd.
- Current Assignee: Bio-Support Co., Ltd.
- Current Assignee Address: KR Gyeonggi-do
- Agency: Ladas & Parry LLP
- Priority: KR10-2007-0039791 20070424; KR10-2008-0037968 20080424
- International Application: PCT/KR2008/002334 WO 20080424
- International Announcement: WO2008/130204 WO 20081030
- Main IPC: C07K16/00
- IPC: C07K16/00 ; C12P21/08
Abstract:
The present invention provides the novel anti-IRC85 monoclonal antibody specifically binding with IRC85 and it showed potent effect in removing the infected/phagocytosed bacteria from THP-I, a monocytic cell that expresses human IRC85 and is infected with Listeria monocytogenes or WR-tubercle bacillus. Accordingly, it can be useful as a medicament and health care food in the prevention and treatment of tuberculosis disease and enteritis disease.
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