Invention Grant
US08445667B2 SiRNA targeting cyclin-dependent kinase inhibitor 1B (p27, Kip1) (CDKN1B)
有权
靶向细胞周期蛋白依赖性激酶抑制剂1B（p27，Kip1）（CDKN1B）
- Patent Title: SiRNA targeting cyclin-dependent kinase inhibitor 1B (p27, Kip1) (CDKN1B)
- Patent Title (中): 靶向细胞周期蛋白依赖性激酶抑制剂1B（p27，Kip1）（CDKN1B）
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Application No.: US13531657Application Date: 2012-06-25
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Publication No.: US08445667B2Publication Date: 2013-05-21
- Inventor: Anastasia Khvorova , Angela Reynolds , Devin Leake , William Marshall , Steven Read , Stephen Scaringe
- Applicant: Anastasia Khvorova , Angela Reynolds , Devin Leake , William Marshall , Steven Read , Stephen Scaringe
- Applicant Address: US CO Lafayette
- Assignee: Dharmacon, Inc.
- Current Assignee: Dharmacon, Inc.
- Current Assignee Address: US CO Lafayette
- Agency: Dorf & Nelson LLP
- Agent Scott D. Locke, Esq.
- Main IPC: C07H21/04
- IPC: C07H21/04 ; C07H21/02
Abstract:
Efficient sequence specific gene silencing is possible through the use of siRNA technology. By selecting particular siRNAs by rational design, one can maximize the generation of an effective gene silencing reagent, as well as methods for silencing genes. Methods, compositions, and kits generated through rational design of siRNAs are disclosed including those directed to nucleotide sequences for CDKN1B.
Public/Granted literature
- US20120264813A1 siRNA Targeting Cyclin-dependent Kinase Inhibitor 1B (p27, Kip1) (CDKN1B) Public/Granted day:2012-10-18
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