Invention Grant
- Patent Title: SiRNA targeting apolipoprotein (APOB)
- Patent Title (中): 靶向载脂蛋白（APOB）的SiRNA
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Application No.: US13536005Application Date: 2012-06-28
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Publication No.: US08445668B2Publication Date: 2013-05-21
- Inventor: Anastasia Khvorova , Angela Reynolds , Devin Leake , William Marshall , Steven Read , Stephen Scaringe
- Applicant: Anastasia Khvorova , Angela Reynolds , Devin Leake , William Marshall , Steven Read , Stephen Scaringe
- Applicant Address: US CO Lafayette
- Assignee: Dharmacon, Inc.
- Current Assignee: Dharmacon, Inc.
- Current Assignee Address: US CO Lafayette
- Agency: Dorf & Nelson LLP
- Agent Scott D. Locke, Esq.
- Main IPC: C07H21/04
- IPC: C07H21/04 ; C07H21/02
Abstract:
Efficient sequence specific gene silencing is possible through the use of siRNA technology. By selecting particular siRNAs by rational design, one can maximize the generation of an effective gene silencing reagent, as well as methods for silencing genes. Methods, compositions, and kits generated through rational design of siRNAs are disclosed including those directed to nucleotide sequences for APOB.
Public/Granted literature
- US20120270926A1 siRNA Targeting Apoliprotein (APOB) Public/Granted day:2012-10-25
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