Invention Grant
- Patent Title: Storage stable perfusion solution for dihydropteridinones
- Patent Title (中): 储存稳定的二氢蝶啶灌注溶液
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Application No.: US12366730Application Date: 2009-02-06
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Publication No.: US08445675B2Publication Date: 2013-05-21
- Inventor: Detlef Mohr , Claus Veit , Fridtjof Traulsen
- Applicant: Detlef Mohr , Claus Veit , Fridtjof Traulsen
- Applicant Address: DE Ingelheim am Rhein
- Assignee: Boehringer Ingelheim International GmbH
- Current Assignee: Boehringer Ingelheim International GmbH
- Current Assignee Address: DE Ingelheim am Rhein
- Agent Michael P. Morris; Anthony P. Bottino
- Priority: DE04019363 20040814
- Main IPC: C07D417/00
- IPC: C07D417/00 ; C07D413/00 ; C70D237/00

Abstract:
Disclosed are storage stable aqueous infusible or injectable solutions containing an active substance of general formula (I) wherein the groups L, R1, R2, R3, R4 and R5 have the meanings given in the claims and in the specification, and an amount of a physiologically acceptable acid or mixture of acids sufficient to dissolve the active substance and act as a stabilizer, optionally together with other formulating excipients suitable for parenteral administration, and a process for preparing the infusible or injectable solutions according to the invention.
Public/Granted literature
- US20090143379A1 Storage stable perfusion solution for dihydropteridinones Public/Granted day:2009-06-04
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