A tamper-evident bottle closure has a ring element affixable to a bottle neck and a cap unit manufactured separately from the ring element and being coupled with the ring element externally to a bottle. The ring element of a coupled closure is affixable to a bottle neck prior to a first time opening of the bottle to retain a contained product in a confirmed sealed condition, yet the cap unit is irreversibly separable from the ring element when unscrewed for a first time to indicate that the bottle has been opened.