Invention Grant
US08454955B2 Methods for treating allergic airway inflammation, airway hypersensitivity, and eosinophilia
有权
用于治疗过敏性气道炎症,气道超敏反应和嗜酸性粒细胞增多的方法
- Patent Title: Methods for treating allergic airway inflammation, airway hypersensitivity, and eosinophilia
- Patent Title (中): 用于治疗过敏性气道炎症,气道超敏反应和嗜酸性粒细胞增多的方法
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Application No.: US12745139Application Date: 2008-08-29
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Publication No.: US08454955B2Publication Date: 2013-06-04
- Inventor: Hiroshi Watarai , Masaru Taniguchi
- Applicant: Hiroshi Watarai , Masaru Taniguchi
- Applicant Address: JP Wako-shi
- Assignee: Riken
- Current Assignee: Riken
- Current Assignee Address: JP Wako-shi
- Agency: Leydig, Voit & Mayer, Ltd.
- Priority: JP2007-307981 20071128
- International Application: PCT/JP2008/065569 WO 20080829
- International Announcement: WO2009/069355 WO 20090604
- Main IPC: A61K39/395
- IPC: A61K39/395

Abstract:
The invention provides a method of screening a therapeutic agent for allergic airway inflammation and/or airway hypersensitivity, comprising using an IL-17RB positive NKT cell, as well as a therapeutic agent for allergic airway inflammation and/or airway hypersensitivity, containing a substance capable of inhibiting or eliminating the Th2 cell-like function of an IL-17RB positive NKT cell as an active ingredient.
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