Invention Grant
- Patent Title: Peroral tablet for bowel cleansing
- Patent Title (中): 口服片剂肠道清洁
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Application No.: US13392605Application Date: 2010-08-27
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Publication No.: US08454995B2Publication Date: 2013-06-04
- Inventor: Masafumi Nomura , Tetsuyuki Nishiyama , Mari Ichikawa , Kyoko Fukaya
- Applicant: Masafumi Nomura , Tetsuyuki Nishiyama , Mari Ichikawa , Kyoko Fukaya
- Applicant Address: JP Tokyo
- Assignee: Zeria Pharmaceutical Co., Ltd.
- Current Assignee: Zeria Pharmaceutical Co., Ltd.
- Current Assignee Address: JP Tokyo
- Agency: Oblon, Spivak, McClelland, Maier & Neustadt, L.L.P.
- Priority: JP2009-199254 20090831
- International Application: PCT/JP2010/005285 WO 20100827
- International Announcement: WO2011/024467 WO 20110303
- Main IPC: A61K9/20
- IPC: A61K9/20

Abstract:
To provide a peroral tablet for bowel cleansing which leaves no remains in the intestinal tract after bowel cleansing, which exhibits a dissolution property equivalent to that of conventional sodium phosphate-containing tablets including crystalline cellulose, and which is a small-size agent readily taken by a subject.The peroral tablet for bowel cleansing containing the following ingredients (A) and (B): (A) 80 to 95 mass % of sodium phosphate, and (B) (B1) 7 to 11 mass % of hydroxypropyl cellulose which has such a particle size that ≧99% of the particles thereof pass through a mesh having an opening of 350 μm and whose 2-mass % aqueous solution has a viscosity of 2.0 to 10.0 mPa.s, (B2) 5 to 13 mass % of hydroxypropyl cellulose which has such a particle size that ≧99% of the particles thereof pass through a mesh having an opening of 150 μm and whose 2-mass % aqueous solution has a viscosity of 3.0 to 5.9 mPa.s, or (B3) 7 to 11 mass % of hydroxypropyl cellulose which has such a particle size that ≧99% of the particles thereof pass through a mesh having an opening of 150 μm and whose 2-mass % aqueous solution has a viscosity of 6.0 to 4,000 mPa.s, and having a water-insoluble ingredient content of 5 mass % or less.
Public/Granted literature
- US20120164219A1 PERORAL TABLET FOR BOWEL CLEANSING Public/Granted day:2012-06-28
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