The present invention relates to printed substrates for use in a variety of applications such as a label stock and flexible packaging structures. The substrates are printed with radiation curable printing ink, especially UV curable printing inks employed in UV inkjet printing processes. The substrates are coated with an ethylene-acrylic acid copolymer based coating capable of adhering and providing wet out properties with UV inkjet inks. Optionally, the coating contains an acrylic polymer. In a specific embodiment, the coating includes a major proportion of ethylene-acrylic acid and minor amounts of filler such as talc and silica. The coating can also include wax and/or pigment such as titanium dioxide. In a further embodiment, the carboxylate groups of the copolymer are neutralized with metal ions from Group Ia, IIa or IIb of the Periodic Table of the Elements, specifically, sodium.