Invention Grant
US08455187B2 Method for isolating a polynucleotide of interest from the genome of a mycobacterium using a BAC-based DNA library: application to the detection of mycobacteria
有权
使用基于BAC的DNA文库从分枝杆菌基因组分离感兴趣的多核苷酸的方法：应用于检测分枝杆菌
- Patent Title: Method for isolating a polynucleotide of interest from the genome of a mycobacterium using a BAC-based DNA library: application to the detection of mycobacteria
- Patent Title (中): 使用基于BAC的DNA文库从分枝杆菌基因组分离感兴趣的多核苷酸的方法：应用于检测分枝杆菌
-
Application No.: US11341914Application Date: 2006-01-30
-
Publication No.: US08455187B2Publication Date: 2013-06-04
- Inventor: Stewart Cole , Roland Buchrieser-Brosch , Stephen Gordon , Alain Billault
- Applicant: Stewart Cole , Roland Buchrieser-Brosch , Stephen Gordon , Alain Billault
- Applicant Address: FR Paris
- Assignee: Institut Pasteur
- Current Assignee: Institut Pasteur
- Current Assignee Address: FR Paris
- Agency: Finnegan, Henderson, Farabow, Garrett & Dunner L.L.P.
- Main IPC: C12Q1/68
- IPC: C12Q1/68 ; C07H19/00 ; C07H21/00
Abstract:
A method for detecting Mycobacterium tuberculosis involves contacting a biological sample with the product of expression of at least one ORF contained in a polynucleotide present in Mycobacterium tuberculosis and absent in Mycabacterium bovis BCG; and detecting whether an immunological complex is formed between the product thereof and antibodies contained in the biological sample, wherein the presence of a complex indicates an infection with Mycobacterium tuberculosis.
Public/Granted literature
Information query
