Invention Grant
- Patent Title: Cell transdifferentiation into brown adipocytes
- Patent Title (中): 细胞转分化成棕色脂肪细胞
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Application No.: US12871209Application Date: 2010-08-30
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Publication No.: US08455191B2Publication Date: 2013-06-04
- Inventor: Paul A. Harding , Zhenqing Zhou
- Applicant: Paul A. Harding , Zhenqing Zhou
- Applicant Address: US OH Oxford
- Assignee: Miami University
- Current Assignee: Miami University
- Current Assignee Address: US OH Oxford
- Agency: Calfee, Halter & Griswold
- Main IPC: C12Q1/68
- IPC: C12Q1/68 ; A61K48/00 ; C07H21/02
Abstract:
A method for converting animal cells into brown adipose tissue cells is provided that includes transforming the animal cells using an expression vector. The expression vector includes a nucleotide sequence encoding HB-EGF operatively linked to a promoter and a nucleotide sequence encoding ADAM 12 operatively linked to a promoter. Converting animal cells to brown adipose tissue cells can be used to treat obesity or to treat cancer by converting target cells to brown adipose tissue cells.
Public/Granted literature
- US20110060034A1 CELL TRANSDIFFERENTIATION INTO BROWN ADIPOCYTES Public/Granted day:2011-03-10
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