Invention Grant
- Patent Title: Immuno-based retargeted endopeptidase activity assays
- Patent Title (中): 基于免疫的重靶向内肽酶活性测定
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Application No.: US12723595Application Date: 2010-03-12
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Publication No.: US08455203B2Publication Date: 2013-06-04
- Inventor: Joanne Wang , Hong Zhu , Dianne D. Hodges , Ester Fernandez-Salas
- Applicant: Joanne Wang , Hong Zhu , Dianne D. Hodges , Ester Fernandez-Salas
- Applicant Address: US CA Irvine
- Assignee: Allergan, Inc.
- Current Assignee: Allergan, Inc.
- Current Assignee Address: US CA Irvine
- Agent Kenton Abel; Debra Condino
- Main IPC: G01N33/53
- IPC: G01N33/53
Abstract:
The present specification discloses SNAP-25 immune response inducing compositions, methods of making α-SNAP-25 antibodies that selectively binds to an epitope comprising a SNAP-25 having a carboxyl-terminus at the P1 residue of the BoNT/A cleavage site scissile bond, α-SNAP-25 antibodies that selectively bind to an epitope comprising a SNAP-25 having a carboxyl-terminus at the P1 residue of the BoNT/A cleavage site scissile bond, methods of detecting retargeted endopeptidase activity, and methods of detecting neutralizing α-re-targeted endopeptidase antibodies.
Public/Granted literature
- US20100233741A1 IMMUNO-BASED RETARGETED ENDOPEPTIDASE ACTIVITY ASSAYS Public/Granted day:2010-09-16
Information query
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