Invention Grant
- Patent Title: ABCB5 positive mesenchymal stem cells as immunomodulators
- Patent Title (中): ABCB5阳性间充质干细胞作为免疫调节剂
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Application No.: US11809790Application Date: 2007-05-31
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Publication No.: US08455245B2Publication Date: 2013-06-04
- Inventor: Markus H. Frank
- Applicant: Markus H. Frank
- Applicant Address: US MA Boston
- Assignee: Children's Medical Center Corporation
- Current Assignee: Children's Medical Center Corporation
- Current Assignee Address: US MA Boston
- Agency: Wolf, Greenfield & Sacks, P.C.
- Main IPC: C12N5/0775
- IPC: C12N5/0775 ; G01N33/53
Abstract:
The present invention is directed to purified preparations of dermal mesenchymal stem cells that are characterized by the cell surface expression of the ABCB5 P-glycoprotein. The cells may be used for any purpose that mesenchymal stem cells from other course are used. For instance they may be administered to treat an organ transplant recipient to improve allograft survival or as a treatment to patients with autoimmune diseases such as multiple sclerosis and rheumatoid arthritis.
Public/Granted literature
- US20080003206A1 ABCB5 positive mesenchymal stem cells as immunomodulators Public/Granted day:2008-01-03
Information query
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