Invention Grant
- Patent Title: Alkyne antagonists of lysophosphatidic acid receptors
- Patent Title (中): 溶血磷脂酸受体的炔烃拮抗剂
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Application No.: US13133636Application Date: 2009-12-10
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Publication No.: US08455499B2Publication Date: 2013-06-04
- Inventor: John Howard Hutchinson , Thomas Jon Seiders , Jeannie M. Arruda
- Applicant: John Howard Hutchinson , Thomas Jon Seiders , Jeannie M. Arruda
- Applicant Address: US NJ Princeton
- Assignee: Amira Pharmaceuticals, Inc.
- Current Assignee: Amira Pharmaceuticals, Inc.
- Current Assignee Address: US NJ Princeton
- Agent Maureen S. Gibbons
- International Application: PCT/US2009/067527 WO 20091210
- International Announcement: WO2010/068775 WO 20100617
- Main IPC: C07D239/26
- IPC: C07D239/26 ; C07D417/10 ; C07D277/10 ; C07D261/14 ; A61K31/426 ; A61K31/422 ; A61K31/42

Abstract:
Described herein are compounds that are antagonists of lysophosphatidic receptor(s). Also described are pharmaceutical compositions and medicaments that include the compounds described herein, as well as methods of using such antagonists, alone and in combination with other compounds, for treating LPA-dependent or LPA-mediated conditions or diseases.
Public/Granted literature
- US20110301134A1 ALKYNE ANTAGONISTS OF LYSOPHOSPHATIDIC ACID RECEPTORS Public/Granted day:2011-12-08
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